Our goal is to understand the mechanisms that regulate voluntary movement and emotion. We also aim to elucidate the pathophysiology of movement disorders such as Parkinson's disease and to develop innovative therapies. Focusing on the basal ganglia, we combine electrophysiological recordings of neuronal activity recordings from animal models with biochemical methods to elucidate neuronal circuit principles. Through a comprehensive approach, from basic science to drug discovery, we hope to advance the understanding and treatment of brain disorders.

Hiromi Sano Associate Professor

I study the functional principles of neural circuits of the mammalian basal ganglia, and the mechanisms by which behavioral changes occur when these circuits are disrupted experimentally or by disease progression in animal models. An understanding of these principles should contribute to the development of treatments for psychiatric and neurological disorders.