International Center for Brain Science, FUJITA HEALTH UNIVERSITY

Division of Neurophysiology

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Projects

Our laboratory uses mice to study the neural mechanisms underlying animal behavior based on sensory preferences by means of electrophysiological measurements and optogenetics. In particular, we focus on the neural pathways that convert tactile sensations into tactile preferences and the neural circuit mechanisms of social behaviors in which social touches play an essential role.

Members

Takayuki Yamashita

Takayuki Yamashita Professor (Neurophysiology)

Dr. Takayuki Yamashita graduated from the Faculty of Agriculture, the University of Tokyo, in 2001, and received his Ph.D. from the Graduate School of Medicine, University of Tokyo, in 2007. After working as a researcher at Swiss Federal Institute of Technology in Lausanne and as an associate professor at Nagoya University, he assumed full professor at Fujita Health University in 2020.

Kansai Fukumitsu

Kansai Fukumitsu Assistant Professor (Neurophysiology)

Dr. Kansai Fukumitsu graduated from the Faculty of Agriculture, Kyoto University, in 2010, and received his Ph.D. from the Graduate School of Biostudies, Kyoto University, in 2015. After working as a researcher at RIKEN Center for Brain Science, he assumed assistant professor at Fujita Health University in 2023.

Main publications

  1.  Li W-R, Nakano T, Mizutani K, Matsubara T, Kawatani M, Mukai Y, Danjo T, Ito H, Aizawa H, Yamanaka A, Petersen CCH, Yoshimoto J, Yamashita T. Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors. Current Biology 33, 3436–3451, 2023.
  2. Fukumitsu K, Kaneko M, Maruyama T, Yoshihara C, Huang AJ, McHugh TJ, Itohara S, Tanaka M, Kuroda KO. Amylin-Calcitonin receptor signaling in the medial   preoptic area mediates affiliative social behaviors in female mice. Nature Communications 13, 709, 2022. 
  3. Matsubara T, Yanagida T, Kawaguchi N, Nakano T, Yoshimoto J, Sezaki M, Takizawa H, Tsunoda SP, Horigane S, Ueda S, Takemoto-Kimura S, Kandori H, Yamanaka A, Yamashita T. Remote control of neural function by X-ray-induced scintillation. Nature Communications 12, 4478, 2021.
  4. Yamashita T, Petersen CCH. Target-specific membrane potential dynamics of neocortical projection neurons during goal-directed behavior. eLife 5, e15798, 2016.
  5. Yamashita T, Pala A, Pedrido L, Kremer Y, Welker E, Petersen CCH. Membrane potential dynamics of neocortical projection neurons driving target-specific signals. Neuron 80, 1477-1490, 2013. 
  6. Yamashita T, Eguchi K, Saitoh N, von Gersdorff H, Takahashi T. Developmental shift to a mechanism of synaptic vesicle endocytosis requiring Ca2+ nanodomain. Nature Neuroscience 13, 838-844, 2010.
  7. Yamashita T, Hige T, Takahashi T. Vesicle endocytosis requires dynamin-dependent GTP hydrolysis at a fast CNS synapse. Science 307, 124-127, 2005.

Information

Division of Neurophysiology（Physiology II, School of Medicine）

Physiology II, School of Medicine

【Address】
#604, 1st building, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan
【Contact】
E-mail：takayuki.yamashita(at)fujita-hu.ac.jp ／ Tel：+81-562-93-2465
※ Please replace “(at)” with “@”.

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