論文等
2024
Ishikawa M, Yamamoto Y, Wulaer B, Kunisawa K, Fujigaki H, Ando T, Kimura H, Kushima I, Arioka Y, Torii Y, Mouri A, Ozaki N, Nabeshima T, Saito K. Indoleamine 2,3-dioxygenase 2 deficiency associates with autism-like behavior via dopaminergic neuronal dysfunction. FEBS J. 291(5):945-964, 2024.
Kurahashi H, Kunisawa K, Mouri A. Social Behavior in Animal Models of Autism Spectrum Disorder. Methods Mol Biol. 2794:331-340, 2024.
Nakamura M, Yoshimi A, Tokura T, Kimura H, Kishi S, Miyauchi T, Iwamoto K, Ito M, Sato-Boku A, Mouri A, Nabeshima T, Ozaki N, Noda Y. Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein. Pain. 165(5):1177-1186, 2024.
Kosuge A, Kunisawa K, Iida T, Wulaer B, Kawai T, Tanabe M, Saito K, Nabeshima T, Mouri A. Chronic social defeat stress induces the down-regulation of the Nedd4L-GLT-1 ubiquitination pathway in the prefrontal cortex of mice. J Neurochem. 2024, in press.
Kurahashi H, Kunisawa K, Mouri A. Social Behavior in Animal Models of Autism Spectrum Disorder. Methods Mol Biol. 2794:331-340, 2024.
Nakamura M, Yoshimi A, Tokura T, Kimura H, Kishi S, Miyauchi T, Iwamoto K, Ito M, Sato-Boku A, Mouri A, Nabeshima T, Ozaki N, Noda Y. Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein. Pain. 165(5):1177-1186, 2024.
Kosuge A, Kunisawa K, Iida T, Wulaer B, Kawai T, Tanabe M, Saito K, Nabeshima T, Mouri A. Chronic social defeat stress induces the down-regulation of the Nedd4L-GLT-1 ubiquitination pathway in the prefrontal cortex of mice. J Neurochem. 2024, in press.
2023
Kubota H, Kunisawa K, Wulaer B, Hasegawa M, Kurahashi H, Sakata T, Tezuka H, Kugita M, Nagao S, Nagai T, Furuyashiki T, Narumiya S, Saito K, Nabeshima T, Mouri A. High salt induces cognitive impairment via the interaction of the angiotensin II-AT1 and prostaglandin E2-EP1 systems. Br J Pharmacol. 180(18):2393-2411, 2023.
Saitoh S, Takaki T, Nakajima K, Wo B, Terashima H, Shimo S, Nguyen HB, Thai TQ, Kumamoto K, Kunisawa K, Nagao S, Tojo A, Ohno N, Takahashi K. Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose co-transporter inhibitors. PLoS One. 18(2):e0281770, 2023.
Mouri A, Hasegawa M, Kunisawa K, Saito K, Nabeshima T. Diagnoses and new therapeutic strategy focused on physiological alteration of tryptophan metabolism. Nihon Yakurigaku Zasshi. 158(3):233-237, 2023.
Zhang X, Kitaichi K, Mouri A, Zhou X, Nabeshima T, Yamada K, Nagai T. An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference. Biochem Biophys Res Commun. 639:100-105, 2023.
Saitoh S, Takaki T, Nakajima K, Wo B, Terashima H, Shimo S, Nguyen HB, Thai TQ, Kumamoto K, Kunisawa K, Nagao S, Tojo A, Ohno N, Takahashi K. Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose co-transporter inhibitors. PLoS One. 18(2):e0281770, 2023.
Mouri A, Hasegawa M, Kunisawa K, Saito K, Nabeshima T. Diagnoses and new therapeutic strategy focused on physiological alteration of tryptophan metabolism. Nihon Yakurigaku Zasshi. 158(3):233-237, 2023.
Zhang X, Kitaichi K, Mouri A, Zhou X, Nabeshima T, Yamada K, Nagai T. An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference. Biochem Biophys Res Commun. 639:100-105, 2023.
2022
Kubota H, Kunisawa K, Niijima M, Hirakawa M, Mori Y, Hasegawa M, Fujigaki S, Fujigaki H, Yamamoto Y, Saito K, Nabeshima T, Mouri A. Deficiency of kynurenine 3-monooxygenase exacerbates impairment of prepulse inhibition induced by phencyclidine. Biochem Biophys Res Commun. 629:142-151, 2022.
Kunisawa K, Shan J, Lu Q, Yang Y, Kosuge A, Kurahashi H, Saito K, Zou L, Nabeshima T, Mouri A. Loureirin C and Xanthoceraside Attenuate Depression-Like Behaviors and Expression of Interleukin-17 in the Prefrontal Cortex Induced by Chronic Unpredictable Mild Stress in Mice. Neurochem Res. 47(9):2880-2889, 2022.
Yang Y, Mouri A, Lu Q, Kunisawa K, Kubota H, Hasegawa M, Hirakawa M, Mori Y, Libo Z, Saito K, Nabeshima T. Loureirin C and Xanthoceraside Prevent Abnormal Behaviors Associated with Downregulation of Brain Derived Neurotrophic Factor and AKT/mTOR/CREB Signaling in the Prefrontal Cortex Induced by Chronic Corticosterone Exposure in Mice. Neurochem Res. 47(9):2865-2879, 2022.
Yamahashi Y, Lin YH, Mouri A, Iwanaga S, Kawashima K, Tokumoto Y, Watanabe Y, Faruk MO, Zhang X, Tsuboi D, Nakano T, Saito N, Nagai T, Yamada K, Kaibuchi K. Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning. Mol Psychiatry. 27(8):3479-3492, 2022.
Lee MT, Mouri A, Kubota H, Lee HJ, Chang MH, Wu CY, Knutson DE, Mihovilovic M, Cook J, Sieghart W, Nabeshima T, Chiou LC. Targeting α6GABAA receptors as a novel therapy for schizophrenia: A proof-of-concept preclinical study using various animal models. Biomed Pharmacother. 150:113022, 2022.
Yoshida M, Hasegawa S, Taniguchi M, Mouri A, Suzuki C, Yoshimi A, Mamiya T, Ozaki N, Noda Y. Memantine ameliorates the impairment of social behaviors induced by a single social defeat stress as juveniles. Neuropharmacology. 217:109208, 2022.
Zhang X, Kitaichi K, Mouri A, Zhou X, Nabeshima T, Yamada K, Nagai T. An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference. Biochem Biophys Res Commun.639:100-105, 2022.
Nakamura M, Yoshimi A, Mouri A, Tokura T, Kimura H, Kishi S, Miyauchi T, Iwamoto K, Ito M, Sato-Boku A, Ozaki N, Nabeshima T, Noda Y. Duloxetine attenuates pain in association with downregulation of platelet serotonin transporter in patients with burning mouth syndrome and atypical odontalgia. Hum Psychopharmacol. 37(2):e2818, 2022.
Kunisawa K, Shan J, Lu Q, Yang Y, Kosuge A, Kurahashi H, Saito K, Zou L, Nabeshima T, Mouri A. Loureirin C and Xanthoceraside Attenuate Depression-Like Behaviors and Expression of Interleukin-17 in the Prefrontal Cortex Induced by Chronic Unpredictable Mild Stress in Mice. Neurochem Res. 47(9):2880-2889, 2022.
Yang Y, Mouri A, Lu Q, Kunisawa K, Kubota H, Hasegawa M, Hirakawa M, Mori Y, Libo Z, Saito K, Nabeshima T. Loureirin C and Xanthoceraside Prevent Abnormal Behaviors Associated with Downregulation of Brain Derived Neurotrophic Factor and AKT/mTOR/CREB Signaling in the Prefrontal Cortex Induced by Chronic Corticosterone Exposure in Mice. Neurochem Res. 47(9):2865-2879, 2022.
Yamahashi Y, Lin YH, Mouri A, Iwanaga S, Kawashima K, Tokumoto Y, Watanabe Y, Faruk MO, Zhang X, Tsuboi D, Nakano T, Saito N, Nagai T, Yamada K, Kaibuchi K. Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning. Mol Psychiatry. 27(8):3479-3492, 2022.
Lee MT, Mouri A, Kubota H, Lee HJ, Chang MH, Wu CY, Knutson DE, Mihovilovic M, Cook J, Sieghart W, Nabeshima T, Chiou LC. Targeting α6GABAA receptors as a novel therapy for schizophrenia: A proof-of-concept preclinical study using various animal models. Biomed Pharmacother. 150:113022, 2022.
Yoshida M, Hasegawa S, Taniguchi M, Mouri A, Suzuki C, Yoshimi A, Mamiya T, Ozaki N, Noda Y. Memantine ameliorates the impairment of social behaviors induced by a single social defeat stress as juveniles. Neuropharmacology. 217:109208, 2022.
Zhang X, Kitaichi K, Mouri A, Zhou X, Nabeshima T, Yamada K, Nagai T. An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference. Biochem Biophys Res Commun.639:100-105, 2022.
Nakamura M, Yoshimi A, Mouri A, Tokura T, Kimura H, Kishi S, Miyauchi T, Iwamoto K, Ito M, Sato-Boku A, Ozaki N, Nabeshima T, Noda Y. Duloxetine attenuates pain in association with downregulation of platelet serotonin transporter in patients with burning mouth syndrome and atypical odontalgia. Hum Psychopharmacol. 37(2):e2818, 2022.
2021
Ito T, Hiramatsu Y, Mouri A, Yoshigai T, Takahashi A, Yoshimi A, Mamiya T, Ozaki N, Noda Y. Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress. Neurosci Res. 171:83-91, 2021.
Noda Y, Soeda K, Uchida M, Goto S, Ito T, Kitagaki S, Mamiya T, Yoshimi A, Ozaki N, Mouri A. Multiple nicotinic acetylcholine receptor subtypes regulate social or cognitive behaviors in mice repeatedly administered phencyclidine. Behav Brain Res. 408:113284, 2021.
Kosuge A, Kunisawa K, Arai S, Sugawara Y, Shinohara K, Iida T, Wulaer B, Kawai T, Fujigaki H, Yamamoto Y, Saito K, Nabeshima T, Mouri A. Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress. Brain Behav Immun. 96:200-211, 2021.
Suento WJ, Kunisawa K, Wulaer B, Kosuge A, Iida T, Fujigaki S, Fujigaki H, Yamamoto Y, Tanra AJ, Saito K, Mouri A, Nabeshima T. Prefrontal cortex miR-874-3p prevents lipopolysaccharide-induced depression-like behavior through inhibition of indoleamine 2,3-dioxygenase 1 expression in mice. J Neurochem. 157(6):1963-1978, 2021.
Wulaer B, Kunisawa K, Hada K, Suento WJ, Kubota H, Iida T, Kosuge A, Nagai T, Yamada K, Nitta A, Yamamoto Y, Saito K, Mouri A, Nabeshima T. Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus. J Neurochem. 157(3):642-655, 2021.
Wulaer B, Kunisawa K, Tanabe M, Yanagawa A, Saito K, Mouri A, Nabeshima T. Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice. Mol Brain. 14(1):43, 2021.
Koizumi H, Hiraga T, Oharomari LK, Hata T, Shima T, Yook JS, Okamoto M, Mouri A, Nabeshima T, Soya H. Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors. Biochem Biophys Res Commun. 534:610-616, 2021.
Mori Y, Mouri A, Kunisawa K, Hirakawa M, Kubota H, Kosuge A, Niijima M, Hasegawa M, Kurahashi H, Murakami R, Hoshi M, Nakano T, Fujigaki S, Fujigaki H, Yamamoto Y, Nabeshima T, Saito K. Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid. Behav Brain Res. 405:113191, 2021.
Li J, Durose WW, Ito J, Kakita A, Iguchi Y, Katsuno M, Kunisawa K, Shimizu T, Ikenaka K. Exploring the factors underlying remyelination arrest by studying the post-transcriptional regulatory mechanisms of cystatin F gene. J Neurochem. 157(6):2070-2090, 2021.
Wulaer B, Kunisawa K, Tanabe M, Yanagawa A, Saito K, Mouri A, Nabeshima T. Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice. Mol Brain. 14(1):43, 2021.
Uchida M, Noda Y, Hasegawa S, Hida H, Taniguchi M, Mouri A, Yoshimi A, Nabeshima T, Yamada K, Aida T, Tanaka K, Ozaki N. Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice. Neurochem Int. 150:105177, 2021.
Noda Y, Soeda K, Uchida M, Goto S, Ito T, Kitagaki S, Mamiya T, Yoshimi A, Ozaki N, Mouri A. Multiple nicotinic acetylcholine receptor subtypes regulate social or cognitive behaviors in mice repeatedly administered phencyclidine. Behav Brain Res. 408:113284, 2021.
Kosuge A, Kunisawa K, Arai S, Sugawara Y, Shinohara K, Iida T, Wulaer B, Kawai T, Fujigaki H, Yamamoto Y, Saito K, Nabeshima T, Mouri A. Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress. Brain Behav Immun. 96:200-211, 2021.
Suento WJ, Kunisawa K, Wulaer B, Kosuge A, Iida T, Fujigaki S, Fujigaki H, Yamamoto Y, Tanra AJ, Saito K, Mouri A, Nabeshima T. Prefrontal cortex miR-874-3p prevents lipopolysaccharide-induced depression-like behavior through inhibition of indoleamine 2,3-dioxygenase 1 expression in mice. J Neurochem. 157(6):1963-1978, 2021.
Wulaer B, Kunisawa K, Hada K, Suento WJ, Kubota H, Iida T, Kosuge A, Nagai T, Yamada K, Nitta A, Yamamoto Y, Saito K, Mouri A, Nabeshima T. Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus. J Neurochem. 157(3):642-655, 2021.
Wulaer B, Kunisawa K, Tanabe M, Yanagawa A, Saito K, Mouri A, Nabeshima T. Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice. Mol Brain. 14(1):43, 2021.
Koizumi H, Hiraga T, Oharomari LK, Hata T, Shima T, Yook JS, Okamoto M, Mouri A, Nabeshima T, Soya H. Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors. Biochem Biophys Res Commun. 534:610-616, 2021.
Mori Y, Mouri A, Kunisawa K, Hirakawa M, Kubota H, Kosuge A, Niijima M, Hasegawa M, Kurahashi H, Murakami R, Hoshi M, Nakano T, Fujigaki S, Fujigaki H, Yamamoto Y, Nabeshima T, Saito K. Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid. Behav Brain Res. 405:113191, 2021.
Li J, Durose WW, Ito J, Kakita A, Iguchi Y, Katsuno M, Kunisawa K, Shimizu T, Ikenaka K. Exploring the factors underlying remyelination arrest by studying the post-transcriptional regulatory mechanisms of cystatin F gene. J Neurochem. 157(6):2070-2090, 2021.
Wulaer B, Kunisawa K, Tanabe M, Yanagawa A, Saito K, Mouri A, Nabeshima T. Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice. Mol Brain. 14(1):43, 2021.
Uchida M, Noda Y, Hasegawa S, Hida H, Taniguchi M, Mouri A, Yoshimi A, Nabeshima T, Yamada K, Aida T, Tanaka K, Ozaki N. Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice. Neurochem Int. 150:105177, 2021.
2020
Kunisawa K, Hatanaka N, Shimizu T, Kobayashi K, Osanai Y, Mouri A, Shi Q, Bhat MA, Nambu A, Ikenaka K. Focal loss of the paranodal domain protein Neurofascin155 in the internal capsule impairs cortically induced muscle activity in vivo. Mol Brain. 13(1):159, 2020.
Wulaer B, Kunisawa K, Kubota H, Suento WJ, Saito K, Mouri A, Nabeshima T. Prefrontal cortex, dorsomedial striatum, and dentate gyrus are necessary in the object-based attention test in mice. Mol Brain. 13(1):171, 2020.
Ito T, Hiramatsu Y, Uchida M, Yoshimi A, Mamiya T, Mouri A, Ozaki N, Noda Y. Involvement of protein kinase C beta1-serotonin transporter system dysfunction in emotional behaviors in stressed mice. Neurochem Int. 140:104826, 2020.
Sakurai M, Yamamoto Y, Kanayama N, Hasegawa M, Mouri A, Takemura M, Matsunami H, Miyauchi T, Tokura T, Kimura H, Ito M, Umemura E, Boku AS, Nagashima W, Tonoike T, Kurita K, Ozaki N, Nabeshima T, Saito K. Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder. Sci Rep. 10(1):1961, 2020.
Noda Y, Uchida M, Mouri A, Yamada S, Goto S, Kitagaki S, Mamiya T, Kushima I, Arioka Y, Ozaki N, Yoshimi A. Involvement of nicotinic acetylcholine receptors in behavioral abnormalities and psychological dependence in schizophrenia-like model mice. Eur Neuropsychopharmacol. 41:92-105, 2020.
Wulaer B, Hada K, Sobue A, Itoh N, Nabeshima T, Nagai T, Yamada K. Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice. Mol Brain. 13(1):170, 2020.
Mouri A, Lee HJ, Mamiya T, Aoyama Y, Matsumoto Y, Kubota H, Huang WJ, Chiou LC, Nabeshima T. Hispidulin attenuates the social withdrawal in isolated disrupted-in-schizophrenia-1 mutant and chronic phencyclidine-treated mice. Br J Pharmacol. 177(14):3210-3224, 2020.
Wulaer B, Kunisawa K, Kubota H, Suento WJ, Saito K, Mouri A, Nabeshima T. Prefrontal cortex, dorsomedial striatum, and dentate gyrus are necessary in the object-based attention test in mice. Mol Brain. 13(1):171, 2020.
Ito T, Hiramatsu Y, Uchida M, Yoshimi A, Mamiya T, Mouri A, Ozaki N, Noda Y. Involvement of protein kinase C beta1-serotonin transporter system dysfunction in emotional behaviors in stressed mice. Neurochem Int. 140:104826, 2020.
Sakurai M, Yamamoto Y, Kanayama N, Hasegawa M, Mouri A, Takemura M, Matsunami H, Miyauchi T, Tokura T, Kimura H, Ito M, Umemura E, Boku AS, Nagashima W, Tonoike T, Kurita K, Ozaki N, Nabeshima T, Saito K. Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder. Sci Rep. 10(1):1961, 2020.
Noda Y, Uchida M, Mouri A, Yamada S, Goto S, Kitagaki S, Mamiya T, Kushima I, Arioka Y, Ozaki N, Yoshimi A. Involvement of nicotinic acetylcholine receptors in behavioral abnormalities and psychological dependence in schizophrenia-like model mice. Eur Neuropsychopharmacol. 41:92-105, 2020.
Wulaer B, Hada K, Sobue A, Itoh N, Nabeshima T, Nagai T, Yamada K. Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice. Mol Brain. 13(1):170, 2020.
Mouri A, Lee HJ, Mamiya T, Aoyama Y, Matsumoto Y, Kubota H, Huang WJ, Chiou LC, Nabeshima T. Hispidulin attenuates the social withdrawal in isolated disrupted-in-schizophrenia-1 mutant and chronic phencyclidine-treated mice. Br J Pharmacol. 177(14):3210-3224, 2020.
2019
Yamasuge W, Yamamoto Y, Fujigaki H, Hoshi M, Nakamoto K, Kunisawa K, Mouri A, Nabeshima T, Saito K. Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma. Cancer Sci. 110(10):3061-3067, 2019.
Lu Q, Mouri A, Yang Y, Kunisawa K, Teshigawara T, Hirakawa M, Mori Y, Yamamoto Y, Libo Z, Nabeshima T, Saito K. Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression. Behav Brain Res. 372:112053, 2019.
Yoshida Y, Fujigaki H, Kato K, Yamazaki K, Fujigaki S, Kunisawa K, Yamamoto Y, Mouri A, Oda A, Nabeshima T, Saito K. Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues. Sci Rep. 9(1):10243, 2019.
Teshigawara T, Mouri A, Kubo H, Nakamura Y, Shiino T, Okada T, Morikawa M, Nabeshima T, Ozaki N, Yamamoto Y, Saito K. Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms. J Affect Disord. 255:168-176, 2019.
Fujigaki H, Mouri A, Yamamoto Y, Nabeshima T, Saito K. Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia. Neurochem Int. 125:1-6, 2019.
Hasegawa S, Yoshimi A, Mouri A, Uchida Y, Hida H, Mishina M, Yamada K, Ozaki N, Nabeshima T, Noda Y. Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Neuropharmacology. 148:107-116, 2019.
Lu Q, Mouri A, Yang Y, Kunisawa K, Teshigawara T, Hirakawa M, Mori Y, Yamamoto Y, Libo Z, Nabeshima T, Saito K. Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression. Behav Brain Res. 372:112053, 2019.
Yoshida Y, Fujigaki H, Kato K, Yamazaki K, Fujigaki S, Kunisawa K, Yamamoto Y, Mouri A, Oda A, Nabeshima T, Saito K. Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues. Sci Rep. 9(1):10243, 2019.
Teshigawara T, Mouri A, Kubo H, Nakamura Y, Shiino T, Okada T, Morikawa M, Nabeshima T, Ozaki N, Yamamoto Y, Saito K. Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms. J Affect Disord. 255:168-176, 2019.
Fujigaki H, Mouri A, Yamamoto Y, Nabeshima T, Saito K. Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia. Neurochem Int. 125:1-6, 2019.
Hasegawa S, Yoshimi A, Mouri A, Uchida Y, Hida H, Mishina M, Yamada K, Ozaki N, Nabeshima T, Noda Y. Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Neuropharmacology. 148:107-116, 2019.
2018
Yamamoto Y, Yamasuge W, Imai S, Kunisawa K, Hoshi M, Fujigaki H, Mouri A, Nabeshima T, Saito K. Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling. Sci Rep. 8(1):15917, 2018.
Kunisawa K, Shimizu T, Kushima I, Aleksic B, Mori D, Osanai Y, Kobayashi K, Taylor AM, Bhat MA, Hayashi A, Baba H, Ozaki N, Ikenaka K. Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability. J Neurochem. 147(3):395-408, 2018.
Hasegawa S, Miyake Y, Yoshimi A, Mouri A, Hida H, Yamada K, Ozaki N, Nabeshima T, Noda Y. Dysfunction of serotoninergic and dopaminergic neuronal systems in the antidepressant-resistant impairment of social behaviors induced by social defeat stress exposure as juveniles. Int J Neuropsychopharmacol. 21(9):837-846, 2018.
Chiou LC, Lee HJ, Ernst M, Huang WJ, Chou JF, Chen HL, Mouri A, Chen LC, Treven M, Mamiya T, Fan PC, Knutson DE, Witzigmann C, Cook J, Sieghart W, Nabeshima T. Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders. Br J Pharmacol. 175:2414-2427, 2018.
Yamazaki M, Yamada H, Munetsuna E, Ishikawa H, Mizuno G, Mukuda T, Mouri A, Nabeshima T, Saito K, Suzuki K, Hashimoto S, Ohashi K. Excess maternal fructose consumption impairs hippocampal function in offspring via epigenetic modification of BDNF promoter. FASEB J. 32:2549-2562, 2018.
Sobue A, Ito N, Nagai T, Shan W, Hada K, Nakajima A, Murakami Y, Mouri A, Yamamoto Y, Nabeshima T, Saito K, Yamada K. Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes. Glia. 66:1034-1052, 2018.
Mouri A, Ukai M, Uchida M, Hasegawa S, Taniguchi M, Ito T, Hida H, Yoshimi A, Yamada K, Kunimoto S, Ozaki N, Nabeshima T, Noda Y. Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis. Neuropharmacology. 133:23-37, 2018.
Kunisawa K, Shimizu T, Kushima I, Aleksic B, Mori D, Osanai Y, Kobayashi K, Taylor AM, Bhat MA, Hayashi A, Baba H, Ozaki N, Ikenaka K. Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability. J Neurochem. 147(3):395-408, 2018.
Hasegawa S, Miyake Y, Yoshimi A, Mouri A, Hida H, Yamada K, Ozaki N, Nabeshima T, Noda Y. Dysfunction of serotoninergic and dopaminergic neuronal systems in the antidepressant-resistant impairment of social behaviors induced by social defeat stress exposure as juveniles. Int J Neuropsychopharmacol. 21(9):837-846, 2018.
Chiou LC, Lee HJ, Ernst M, Huang WJ, Chou JF, Chen HL, Mouri A, Chen LC, Treven M, Mamiya T, Fan PC, Knutson DE, Witzigmann C, Cook J, Sieghart W, Nabeshima T. Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders. Br J Pharmacol. 175:2414-2427, 2018.
Yamazaki M, Yamada H, Munetsuna E, Ishikawa H, Mizuno G, Mukuda T, Mouri A, Nabeshima T, Saito K, Suzuki K, Hashimoto S, Ohashi K. Excess maternal fructose consumption impairs hippocampal function in offspring via epigenetic modification of BDNF promoter. FASEB J. 32:2549-2562, 2018.
Sobue A, Ito N, Nagai T, Shan W, Hada K, Nakajima A, Murakami Y, Mouri A, Yamamoto Y, Nabeshima T, Saito K, Yamada K. Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes. Glia. 66:1034-1052, 2018.
Mouri A, Ukai M, Uchida M, Hasegawa S, Taniguchi M, Ito T, Hida H, Yoshimi A, Yamada K, Kunimoto S, Ozaki N, Nabeshima T, Noda Y. Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis. Neuropharmacology. 133:23-37, 2018.
2017
Matsumoto Y, Niwa M, Mouri A, Noda Y, Fukushima T, Ozaki N, Nabeshima T. Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice. Psychopharmacology (Berl). 234(20):3055-3074, 2017.
Mouri A, Noda Y, Niwa M, Matsumoto Y, Mamiya T, Nitta A, Yamada K, Furukawa S, Iwamura T, Nabeshima T. 25. The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization. Behav Brain Res. 329:157-165, 2017.
Kunisawa K, Kido K, Nakashima N, Matsukura T, Nabeshima T, Hiramatsu M. Betaine attenuates memory impairment after water-immersion restraint stress and is regulated by the GABAergic neuronal system in the hippocampus. Eur J Pharmacol. 796:122-130, 2017.
Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K. Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice. Immunol Lett. 181:94-100, 2017.
Tashiro T, Murakami Y, Mouri A, Imamura Y, Nabeshima T, Yamamoto Y, Saito K. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions. Behav Brain Res. 317:279-285, 2017.
Mouri A, Noda Y, Niwa M, Matsumoto Y, Mamiya T, Nitta A, Yamada K, Furukawa S, Iwamura T, Nabeshima T. 25. The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization. Behav Brain Res. 329:157-165, 2017.
Kunisawa K, Kido K, Nakashima N, Matsukura T, Nabeshima T, Hiramatsu M. Betaine attenuates memory impairment after water-immersion restraint stress and is regulated by the GABAergic neuronal system in the hippocampus. Eur J Pharmacol. 796:122-130, 2017.
Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K. Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice. Immunol Lett. 181:94-100, 2017.
Tashiro T, Murakami Y, Mouri A, Imamura Y, Nabeshima T, Yamamoto Y, Saito K. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions. Behav Brain Res. 317:279-285, 2017.